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pentobarbital will boost the amount or result of ivosidenib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of ivosidenib with powerful CYP3A4 inducers lessened ivosidenib plasma concentrations.pentobarbital will decrease the extent or impact of glecaprevir/pibrentasvir by influencing